Sarah graduated from Colorado State University in 2014 with a BS in Biomedical Sciences. During college, she worked in the laboratory of Dr. Dawn Duval measuring IGF2BP1 promoter activity in human and canine osteosarcoma cell lines. She entered the IBMG program in 2014 and joined the Mosley and Harrington labs in May of 2015 and is planning to defend in Spring 2020. Early on, her project focused on early elongation control of RNAPII transcription in both Saccharomyces cerevisiae and mammals. Her thesis work involves the development of a novel method for investigating how mutations within a protein can affect the rest of the cell. Many diseases are caused by mutations within a single protein, and prior to this novel application of a recently emerging method, there was no efficient way to study how one protein disrupts cellular homeostasis, leaving a gap in the ability to link genotype to phenotype. This method provides a way to characterize global changes in protein stability and interactions and is now being transitioned into human disease models with the hope that the method may eventually be adapted for use in discovering the underlying mechanistic causes of disease. Sarah successfully defended her PhD thesis in April 2020 and accepted a position at Taylor University as an Assistant Professor of Biology.

Jose Fabian Victorino the IV completed his undergraduate education at University of California Irvine in 2010 managing to have a one summer research experience studying transposable elements after his graduation. After taking a year off to meditate Jose realized his only true path could be to investigate the vast mysteries occurring within our cells. Jose received an M.Sc. degree at California State University Dominguez Hills researching a variety of topics including breast/pancreatic cancer, erectile dysfunction, and a brief stint working with “thief” ants in the Rainforests of Costa Rica. Jose Realized that to get to the real answers of biology he had to go smaller, yet bigger!, and study the even tinier entities inside of the nucleus of our cells known as DNA and RNA. Currently Jose is studying the mechanisms of elongation and termination, specifically looking at a model of “Early termination” through the NNS pathway using tools and methods such as genomics, proteomics, and good old biochemistry and molecular biology techniques. Jose also enjoys playing tennis on the club team at IUPUI, woodworking and spending time outdoors. Jose succesfully defended his PhD thesis January 2020, and accepted a postdoctoral position the Translational Genomics Research institute (TGen). 

Melanie received a BA in Biology from Bluffton University in Bluffton, Ohio in 2008. She then joined IUSM as a research technician in the Department of Medical and Molecular Genetics studying telomerase regulation with Dr. Brittney-Shea Herbert. In 2010, she entered the IBMG program and joined the Mosley Lab in 2011. Melanie has studied the roles of Rrp6 and Rtr1 in the termination of short RNAPII transcripts, earning her PhD in 2015 and continuing as a Postdoc. As a grad student, Melanie founded the nonprofit, Central Indiana Science Outreach, which organizes fun science events for adults and professional development opportunities for early career researchers. She enjoys sharing her love of fundamental biology, dinosaurs, and astronomy, playing with her two dogs and nephew, hiking, biking, watching Sci-fi, and exploring Indianapolis.

Links: 

cinsoindy.org 

http://www.facebook.com/CentralIndianaScienceOutreach

Twitter: @meljoyfox @CINSOindy

Jerry graduated with his BS and MS from Youngstown State University.  He joined the Mosley lab in 2010 as a research technician and full-time as a PhD graduate student in 2011.  He finished his PhD research in 2016 which centered around how reversible phosphorylation of RNAPII by the atypical phosphatase Rtr1 affects transcription elongation and histone methylation.

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Neil graduated from Rose-Hulman Institute of Technology in 2000 with a BS in Chemical Engineering. He has worked in a variety of engineering related roles in the pharmaceutical and medical devices industry. His experiences have included incineration process engineering, small molecule development, medical device process engineering, and large molecule biotech process development. He is married to his best friend and has two kids. He enrolled in the IUSM biochem/molecular biology master’s program in 2014 working in Mosley lab and at a nearby pharmaceutical company, to successfully defend his master's thesis. He likes making and drinking beer.

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Asha earned her BA in Biochemistry in 2015 from DePauw University. While at DePauw, she spent a total of three semesters researching under Professor Lynn Bedard, where she was introduced to a collaborative work with the Mosley Lab. Following independent research through school and an 8-week summer internship, Asha was hired to work a lab technician in the Mosley Lab while completing her MS in Cellular and Integrative Physiology.

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